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- W2373579423 abstract "Objective:To evaluate the value and correlation of N-terminal probrain natriuretic peptide(NT-proBNP) and Matrix Metalloproteinase -9(MMP-9)in early ventricular remodeling in non-ST elevation acute coronary syndrome(ACS). Methods:A total of 57 consecutive patients with non-ST elevation ACS were recruited and classified in 3 groups:High risk group(n=17),Intermediate risk group(n=15) and Low risk group(n=25);in addition,29 healthy individuals were served as Control group.The levels of serum NT-proBNP and MMP-9 were respectively examined before coronary angiography. Echocardiogram was performed before and after the angiography to evaluate the ventricular remodeling and heart function. Results:There were significant differences between the levels of NT-proBNP,MMP-9,the values of ejection fraction(EF) and left ventricular mass index(LVMI) in different groups,while not much difference was found in EF between Intermediate risk group and Low risk group.In High-risk group,NT-proBNP level was positively related to MMP-9 concentration(r=0.574,P= 0.025);NT-proBNP level was positively related to LVMI value(r=0.617,P=0.014);MMP-9 level was negatively related to EF value(r=-0.542,P=0.025). Conclusion:The combination testing of NT-proBNP and MMP-9 had crucial meaning for detection of early ventricular remodeling in high-risk non-ST elevation ACS." @default.
- W2373579423 created "2016-06-24" @default.
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- W2373579423 date "2009-01-01" @default.
- W2373579423 modified "2023-10-04" @default.
- W2373579423 title "N-Terminal Probrain Natriuretic Peptide and Matrix Metalloproteinase-9 in Early Ventricular Remodeling of Non-ST Elevation Acute Coronary Syndrome" @default.
- W2373579423 hasPublicationYear "2009" @default.
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