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- W2373587802 abstract "Objective To study the brain edema and the protein expressions of Fas-associated with death domain protein(FADD) and apoptosis in rats with intracerebral hemorrhage,and the effects of erythropoietin on them.Methods Male SD rats were randomly divided into three groups: Sham-operated group,EPO treatment group,intracerebral hemorrhage group.The model of ICH was established in rats by intracerebral injection of autogenous blood.The protein expressions of FADD were detected by immunohisto-chemistry,the apoptosis was measured with TUNEL.Brain edema were assayed by dry/wet weight method.Results The brain water contented,expressions of FADD and number of apoptosis cell in the region around hematoma in EPO group was significantly decreased compared with model group.Conclusion EPO can significantly reduce brain edema and the expressions of FADD,apoptosis cells,protect the brain after intracerebral hemorrhage." @default.
- W2373587802 created "2016-06-24" @default.
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- W2373587802 date "2013-01-01" @default.
- W2373587802 modified "2023-09-23" @default.
- W2373587802 title "The studies of the neuroprotective effect and mechanism about EPO on rats with intracerebral hemorrhage" @default.
- W2373587802 hasPublicationYear "2013" @default.
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