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- W2373589124 abstract "Objective: To study the genetic polymorphisms of methylenetrahydrofolate reductase(MT-HFR) among the Uygur and Han populations in Xinjiang and to gain genetic data for establishment of genetic polymorphism bank of Xinjiang Minorities.Methods: The technique of polymerase chain reaction and restriction fragment length polymorphism(PCR-RFLP) was usded to detect the genotype and allele frequencies at 1298 mononucleotide sites of MTHFR among the Uygur and Han populations in Xinjiang.Results: At the site of 1298,the C allele frenquencies were found to be 12% and 23% respectively for the Uygur and the Han populations,P0.05,which had statistical differences.The C allele frequencies at 1298 mononucleotide sites of MTHFR among the Uygur in Xinjiang had statistical differences with those hitherto reported Miao,Buyi populations in Guizhou.Conclusion: The polymorphisms of the 1298 mononucleotide sites of MTHFR were diverse in different populations.The C allele frequencies at the site of MTHFR1298 was differneret in the Uygur and Han population in Xinjiang.The C allele frequencies at 1298 mononucleotide sites of MTHFR among the Uygur in xinjiang was different with Miao and Buyi populations in Guizhou because of different nations." @default.
- W2373589124 created "2016-06-24" @default.
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- W2373589124 date "2012-01-01" @default.
- W2373589124 modified "2023-09-25" @default.
- W2373589124 title "5,10-Methylenetetrahydrofolate Reductase Polymorphism in Uygur and Han Nationalities in Xinjiang" @default.
- W2373589124 hasPublicationYear "2012" @default.
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