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- W2373603600 abstract "Objective To study the changes of cerebrospinal fluid levels of nitric oxide(NO) and tumor necrosis factor-α(TNF-α) in children with viral encephalitis and their significance.Methods The cerebuospinal fluid levels of TNF-α in children with viral encephalitis were detected with enzyme-linked immunoadsorbent assay(ELISA)method and the NO levels were detected with colorimetric method when the patients were in acute stage and convalescent peiod.And the NO and TNF-α levels of cerebrospinal fluid were detecte in 20 normal children undergoing anesthetized operation without organic injury in certral nervour system at the same peild.Results The cerebrospinal fluid levels of NO and TNF- α of the patients in acute stage were significantly higher than those of the control group(all P0.01).The cerebrospinal fluid levels of NO and TNF-α of the serious patient were significantly higher than those of the mild patients (P0.01).The NO and TNF-α levels were positively correlated with the patient's copdition and their levels in acute stage were significantly higher than those of the cases in convalescent stage (all P0.01).Conclusion The cerebrospi- nal fluid levels of NO and TNF-α in the children with viral encephalitis raise significantly,their levels in children connected significantly with the advance and the condition of viral encephalitis. They partici- pate in the advance of viral encephalitis." @default.
- W2373603600 created "2016-06-24" @default.
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- W2373603600 date "2006-01-01" @default.
- W2373603600 modified "2023-09-26" @default.
- W2373603600 title "Changes of cerebrospinal fluid levels of nitric oxide and tumor necrosis factor-α in children with viral encephalitis and their significance" @default.
- W2373603600 hasPublicationYear "2006" @default.
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