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- W2373654232 abstract "Objective To observe the effect of intensive lipid-lowering therapy on blood-fat and carotid atherosclerosis in patients with cerebral ischemic stroke.Methods 102 patients with dyslipidemia and carotid atherosclerosis were randomly divided into atorvastatin routine treatment group(20mg/d)and intensive lipid-lowering treatment group(40mg/d),51 cases patients in each group.Blood lipid was tested and the carotid intima-media thickness(CIMT)change was determined before and after 6 months respectively.Results 6 months after treatment,the two groups of total cholesterol(TC),low density lipoprotein(LDL-C),triglycerides(TG)levels were reduced,high-density lipoprotein cholesterol(HDL-C)were raised.Intensive lipid-lowering group compared with conventional lipid-lowering group,blood fat change was more obvious(P0.05 or P0.01).The CIMT and plaque area in Iintensive lipid-lowering group were lowerer than the conventional treatment group obviously(P0.05).The recurrence rate of ischemic cerebrovascular disease in intensive lipid-lowering group was lowerer than conventional group significantly(P0.05).Adverse reaction rate was no statistical significance in two groups.Conclusion Intensive lipid-lowering therapy can effectively improve blood lipid level,effectively delay and reverse carotid atherosclerotic plaques,and reduce ischemic cerebrovascular recurrence rate of the ischemic stroke patients with safety." @default.
- W2373654232 created "2016-06-24" @default.
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- W2373654232 date "2013-01-01" @default.
- W2373654232 modified "2023-09-23" @default.
- W2373654232 title "Effect of intensive lipid lowering on blood-fat and carotid atherosclerosis in patients with cerebral ischemic stroke" @default.
- W2373654232 hasPublicationYear "2013" @default.
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