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- W2373663889 abstract "Objective To investigate the role of abnormal claudin-1 protein expression in the pathogenesis of large intestine cancer.Methods Immunohistochemistry was used to detect the differential protein expression between 102 cases of large intestine cancer and 42 cases of normal large intestine.The relationship between the abnormal claudin-1 expression and the clinical features was assessed by statistical analysis.Results Compared with normal large intestine samples,the claudin-1 protein expression was markedly increased in large intestine cancer samples(P0.01).The increased claudin-1 protein expression was associated with Dukes staging(P=0.035)and metastasis(P=0.040)of large intestine cancer.Conclusion The large intestine cancer samples show higher claudin-1 expression,which might be related to the staging and metastasis of the disease." @default.
- W2373663889 created "2016-06-24" @default.
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- W2373663889 date "2010-01-01" @default.
- W2373663889 modified "2023-09-28" @default.
- W2373663889 title "Claudin-1 Protein Expression in Large Intestine Cancer and Its Related Significance" @default.
- W2373663889 hasPublicationYear "2010" @default.
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