Matches in SemOpenAlex for { <https://semopenalex.org/work/W2373669396> ?p ?o ?g. }
Showing items 1 to 47 of
47
with 100 items per page.
- W2373669396 abstract "Objective To synthesize glycyrrhetinic acid derivatives and improve its biological activities according to the structure activity relationship of glycyrrhetinc acid. Methods The N-Cyclohexyl-glycyrrhetinic acid amide derivatives were synthesized in the presence of DCC,HOBT/DMAP with 18β-Glycyrrhetinic acid,11-deoxyglycyrrhetinic acid and Cyclohexylamine as starting materials.The anti-inflammatory activity of N-Cyclohexyl-glycyrrhetinic acid amide was studied. Results The synthesized compounds were confirmed by IR,1HNMR and MS and N-Cyclohexyl-glycyrrhetinic acid amide possessed higher anti-inflammatory activity than that of the reference drug hydrocortisone. Conclusion Two glycyrrhetinic acid derivatives were synthesized in this research and enriched the kinds of glycyrrhetinic acid derivatives.The N-Cyclohexyl-glycyrrhetinic acid amide possesses higher anti-inflammatory activity than hydrocortisonedoes,thus providing the new candidates for anti-inflammatory drug screening." @default.
- W2373669396 created "2016-06-24" @default.
- W2373669396 creator A5057382778 @default.
- W2373669396 date "2012-01-01" @default.
- W2373669396 modified "2023-09-23" @default.
- W2373669396 title "Synthesis and Anti-inflammatory Activity of N-cyclohexyl-Glycyrrhetinic Acid Amide" @default.
- W2373669396 hasPublicationYear "2012" @default.
- W2373669396 type Work @default.
- W2373669396 sameAs 2373669396 @default.
- W2373669396 citedByCount "0" @default.
- W2373669396 crossrefType "journal-article" @default.
- W2373669396 hasAuthorship W2373669396A5057382778 @default.
- W2373669396 hasConcept C178790620 @default.
- W2373669396 hasConcept C185592680 @default.
- W2373669396 hasConcept C2778439535 @default.
- W2373669396 hasConcept C71240020 @default.
- W2373669396 hasConceptScore W2373669396C178790620 @default.
- W2373669396 hasConceptScore W2373669396C185592680 @default.
- W2373669396 hasConceptScore W2373669396C2778439535 @default.
- W2373669396 hasConceptScore W2373669396C71240020 @default.
- W2373669396 hasLocation W23736693961 @default.
- W2373669396 hasOpenAccess W2373669396 @default.
- W2373669396 hasPrimaryLocation W23736693961 @default.
- W2373669396 hasRelatedWork W1978453782 @default.
- W2373669396 hasRelatedWork W1983003946 @default.
- W2373669396 hasRelatedWork W2006040128 @default.
- W2373669396 hasRelatedWork W2035823841 @default.
- W2373669396 hasRelatedWork W2044392763 @default.
- W2373669396 hasRelatedWork W2055076896 @default.
- W2373669396 hasRelatedWork W2085749744 @default.
- W2373669396 hasRelatedWork W2087964158 @default.
- W2373669396 hasRelatedWork W2128256479 @default.
- W2373669396 hasRelatedWork W2142575997 @default.
- W2373669396 hasRelatedWork W2356481555 @default.
- W2373669396 hasRelatedWork W2365056516 @default.
- W2373669396 hasRelatedWork W2390880921 @default.
- W2373669396 hasRelatedWork W2392137713 @default.
- W2373669396 hasRelatedWork W2407897058 @default.
- W2373669396 hasRelatedWork W2410747851 @default.
- W2373669396 hasRelatedWork W2950815320 @default.
- W2373669396 hasRelatedWork W3028123488 @default.
- W2373669396 hasRelatedWork W2821619480 @default.
- W2373669396 hasRelatedWork W2822794597 @default.
- W2373669396 isParatext "false" @default.
- W2373669396 isRetracted "false" @default.
- W2373669396 magId "2373669396" @default.
- W2373669396 workType "article" @default.