Matches in SemOpenAlex for { <https://semopenalex.org/work/W2373682021> ?p ?o ?g. }
- W2373682021 endingPage "8" @default.
- W2373682021 startingPage "1" @default.
- W2373682021 abstract "Dynamic (latent or/and labile) obstruction of left ventricular outflow (LVOT) was recognized from the earliest clinical descriptions of hypertrophic cardiomyopathy (HCM) and has proved to be a complex phenomenon, as well as arguably the most audible (“visible”) pathophysiological hallmark of this heterogeneous disease. The aim of the current review is focused on two novel issues in a subgroup of obstructive HCM. Firstly, the important methodological problem in HCM is the examination of a subgroup of patients with nonobstructive hypertrophy in resting conditions and hard, but possible provoking obstruction. Recently, investigators have proposed physiological stress test (with double combined stimuli) to disclose such type of patients. The upright exercise is described in the ESC guideline on hypertrophic cardiomyopathy from 2014 and may appear as a candidate for gold standard provocation test. The second novel area of interest is associated with elevated level of signaling biomarkers: hypercoagulation, hemolysis, acquired von Willebrand 2A disease, and enhanced oxidative stress. The accelerated and turbulent flow within narrow LVOT may be responsible for these biochemical disturbances. The most recent advances in the treatment of obstructive HCM are related to nonpharmacological methods of LVOT gradient reduction. This report extensively discusses novel methods." @default.
- W2373682021 created "2016-06-24" @default.
- W2373682021 creator A5006091397 @default.
- W2373682021 creator A5082600585 @default.
- W2373682021 date "2016-01-01" @default.
- W2373682021 modified "2023-10-06" @default.
- W2373682021 title "Obstructive Form of Hypertrophic Cardiomyopathy-Left Ventricular Outflow Tract Gradient: Novel Methods of Provocation, Monitoring of Biomarkers, and Recent Advances in the Treatment" @default.
- W2373682021 cites W1047250547 @default.
- W2373682021 cites W111817915 @default.
- W2373682021 cites W1552839040 @default.
- W2373682021 cites W1678946474 @default.
- W2373682021 cites W168508249 @default.
- W2373682021 cites W1841801981 @default.
- W2373682021 cites W1846550110 @default.
- W2373682021 cites W1867545177 @default.
- W2373682021 cites W1896370762 @default.
- W2373682021 cites W1942480072 @default.
- W2373682021 cites W1963625358 @default.
- W2373682021 cites W1966734856 @default.
- W2373682021 cites W1966944760 @default.
- W2373682021 cites W1968233035 @default.
- W2373682021 cites W1970573184 @default.
- W2373682021 cites W1971650982 @default.
- W2373682021 cites W1973822306 @default.
- W2373682021 cites W1983376023 @default.
- W2373682021 cites W1986636360 @default.
- W2373682021 cites W1994772134 @default.
- W2373682021 cites W2000424026 @default.
- W2373682021 cites W2009768143 @default.
- W2373682021 cites W2015576244 @default.
- W2373682021 cites W2029964994 @default.
- W2373682021 cites W2036162164 @default.
- W2373682021 cites W2037971966 @default.
- W2373682021 cites W2047066352 @default.
- W2373682021 cites W2047097438 @default.
- W2373682021 cites W2048174976 @default.
- W2373682021 cites W2056231293 @default.
- W2373682021 cites W2061157652 @default.
- W2373682021 cites W2061545182 @default.
- W2373682021 cites W2068967760 @default.
- W2373682021 cites W2069737917 @default.
- W2373682021 cites W2076513253 @default.
- W2373682021 cites W2076537391 @default.
- W2373682021 cites W2078603316 @default.
- W2373682021 cites W2083366576 @default.
- W2373682021 cites W2087926690 @default.
- W2373682021 cites W2094515467 @default.
- W2373682021 cites W2097618980 @default.
- W2373682021 cites W2119019445 @default.
- W2373682021 cites W2119045744 @default.
- W2373682021 cites W2120108477 @default.
- W2373682021 cites W2122140035 @default.
- W2373682021 cites W2127913903 @default.
- W2373682021 cites W2138256953 @default.
- W2373682021 cites W2139785292 @default.
- W2373682021 cites W2140174056 @default.
- W2373682021 cites W2141524565 @default.
- W2373682021 cites W2141586938 @default.
- W2373682021 cites W2144321027 @default.
- W2373682021 cites W2144393548 @default.
- W2373682021 cites W2153151839 @default.
- W2373682021 cites W2159134334 @default.
- W2373682021 cites W2160886677 @default.
- W2373682021 cites W2165296177 @default.
- W2373682021 cites W2178490686 @default.
- W2373682021 cites W2198669484 @default.
- W2373682021 cites W2200935196 @default.
- W2373682021 cites W2202055592 @default.
- W2373682021 cites W2229279613 @default.
- W2373682021 cites W2233527287 @default.
- W2373682021 cites W2308249738 @default.
- W2373682021 cites W2310870987 @default.
- W2373682021 cites W2320801435 @default.
- W2373682021 cites W2345290867 @default.
- W2373682021 cites W2380592807 @default.
- W2373682021 cites W2404608663 @default.
- W2373682021 cites W2416258730 @default.
- W2373682021 cites W4246281088 @default.
- W2373682021 cites W96419741 @default.
- W2373682021 doi "https://doi.org/10.1155/2016/1575130" @default.
- W2373682021 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4877458" @default.
- W2373682021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27247935" @default.
- W2373682021 hasPublicationYear "2016" @default.
- W2373682021 type Work @default.
- W2373682021 sameAs 2373682021 @default.
- W2373682021 citedByCount "9" @default.
- W2373682021 countsByYear W23736820212017 @default.
- W2373682021 countsByYear W23736820212019 @default.
- W2373682021 countsByYear W23736820212020 @default.
- W2373682021 countsByYear W23736820212022 @default.
- W2373682021 crossrefType "journal-article" @default.
- W2373682021 hasAuthorship W2373682021A5006091397 @default.
- W2373682021 hasAuthorship W2373682021A5082600585 @default.
- W2373682021 hasBestOaLocation W23736820211 @default.
- W2373682021 hasConcept C110586980 @default.
- W2373682021 hasConcept C126322002 @default.
- W2373682021 hasConcept C142724271 @default.
- W2373682021 hasConcept C164705383 @default.