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- W2373684688 abstract "Objective:To investigate whether the application of radiofrequency catheter ablation (RFCA) might induce a prethrombotic state,we study the biochemicalmarkers of prethrombotic state ,including platelet membrane protein CD62P,Ⅱb/Ⅲa,prothrombin (PT) and fibrinogen(FIB) before and after RFCA. Method:Sixty-seven patients with supraventricular tachycardia were enrolled in the study.Serial determinations of the percentage of actived platelets CD62P and Ⅱb/Ⅲa were made at the time insertion of venious sheaths and before the catheter insert(Ⅰ),after electrophysiologic study(EPS)(Ⅱ),immediately after RFCA(Ⅲ),24 hours after RFCA(Ⅳ), after 48 hours (Ⅴ) by flow cytometry.The plasma levels of PT and FIB were measured at the time point Ⅰ, Ⅳ with the means of ACL. Heparin was given during the operation by artery accessory pathways.Result:Compared with the baseline, the percentage of activated platelets CD62P and Ⅱb/Ⅲa increased significantly at the end of RFCA (P0.05), and no significance between with heparin and no-heparin.There were no significance between the levels of PT and FIB at the time point Ⅰ, Ⅳ (P0.05). Conclusion: The procedure of radiofrequency catheter ablation can induce a prethrombotic state." @default.
- W2373684688 created "2016-06-24" @default.
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- W2373684688 date "2006-01-01" @default.
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- W2373684688 title "Radiofrequency catheter ablation and prethrombotic state" @default.
- W2373684688 hasPublicationYear "2006" @default.
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