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- W2373697430 abstract "Objective: To explore the effect of thyroid hormone on carotid artery atherosclerosis in type 2 diabetes mellitus (T2DM) patients with euthyroidism. Methods: According to results of carotid artery color Doppler ultrasound, 248 T2DM patients were divided into four groups, 92 patients without stenosis (control group), 32 patients with stenosis30% (mild stenosis group), 93 patients with 30%≤stenosis70% (moderate stenosis group) and 31 patients with stenosis≥70% (severe stenosis group). Results of Doppler ultrasound and levels of serum thyroid hormone were analyzed in four groups. Results: There were significantly lower values of serum triiodothyronine (FT3) and high-density lipoprotein(HDL-C)in severe stenosis group than those of other three groups. The values of trigalloyl glycerol (TG), total cholesterol (TC), low density lipoprotein-cholesterol(LDL-C) and systolic blood pressure (SBP) were significantly higher in severe stenosis group than those of other three groups. Values of FT3 and HDL-C were significantly lower in mild stenosis group, moderate stenosis group and severe stenosis group than those of control group (P 0.01 or P 0.05). The carotid artery atherosclerosis was negatively correlated with levels of FT3 and HDL-C. The increased levels of FT3 and HDL-C were independent protective factors for the carotid artery. The age and increased TG were independent risk factors involved in the severity of carotid artery atherosclerosis. Conclusion: FT3 within a normal level might be a protection factor for atherosclerosis in patients with T2DM." @default.
- W2373697430 created "2016-06-24" @default.
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- W2373697430 date "2012-01-01" @default.
- W2373697430 modified "2023-09-28" @default.
- W2373697430 title "The Effect of Thyroid Hormones on Carotid Artery Atherosclerosis in Patients with Type 2 Diabetes Mellitus" @default.
- W2373697430 hasPublicationYear "2012" @default.
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