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- W2373721610 abstract "In order to investigate the role of β-endorphin in the regulation of immune function,we ob-served in vitro and in vivo effects of β-endorphinon on mitogen--induced spleen lymphocyte pro-liferation,interleukin—1 and interleukin—2 production,It was found that β-endorphin at 10~(-8)-10~(-14)mol/L could enhance Con A induced proliferation and interleukin-2 production of spleniclymphocyte in vitro.B—endprphin couled also increase LPS induced interleukin—1 productionby peritoneal macropages.The augmentative effect of β-endorphin on lymphocyte proliferationand interleukin—2 production was abrogate by naloxone.Intravenous injection of β—endorphinalso increased the lymphoproliferation,interleukin—1 and interleukin—2 production.Our resultsindicated that β-endorphin enhanced immune function of rats and this action of β-endorphin maybemediated by opioid receptor." @default.
- W2373721610 created "2016-06-24" @default.
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- W2373721610 date "1993-01-01" @default.
- W2373721610 modified "2023-09-23" @default.
- W2373721610 title "The effect of betaendorphin on immune function of rats" @default.
- W2373721610 hasPublicationYear "1993" @default.
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