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• W2373752190 abstract "Objective:To evaluate the noninvasive positive ventilation(NIPPV)in weaning of invasive positive ventilation(IPPV) for patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:The clinical data of patients with AECOPD receiving invasive positive ventilation(IPPV)48 hours(orointubation or nasointubation) in Huangpu Central Hospital in Shanghai were collected prospectively(prospective group) during December 1 of 2007 to March 10 of 2008.They were extubated to receiving NIPPV after spontaneous breathing trials(SBTs) for 120min only one time as their conditions became stable.while the clinical data from another group of patients with AECOPD in same Department during July 1 of 2006 to November 30 of 2007 were collected.They received SBTs for 30～120min twice a day as their condition became stable and the SBTs was prolonged day by day until lasted for 24 hours.As their condition became stable they were extubated with no NIPPV sequentially.The age,APACHE II score,the duration of IPPV(d),mean artery pressure(mmHg),hear rate(HR),respiratory rate(RR),arterial blood gas analysis,the duration of intubation and stay in ICU,reintubation rates,extubation successful rates,morbidity of ventilation associated pneumonia(VAP)and mortality for patients of both groups were compared respectively.Results:There were 15 cases in prospective group with 8/7 cases of male/female,82±4.93 years old of age and 24.9±3.3 of APACHE II scores.There were 16 cases in retrospective group with 10/6 cases of male/female,79.56±8.39 years old of age and 26.69±3.94 of APACHE II scores.There were no significant difference between two groups for their age and APACHE II scores(P0.05).The same as duration of IPPV(d),mean artery pressure(mmHg),HR,RR,arterial blood gas analysis when SBTs beginning with.But there were significant difference(P0.05)between two groups for their duration of intubation and stay in ICU,reintubation rates,extubation successful rates,morbidity of VAP and mortality.The duration of intubation and stay in ICU of patients in prospective group were more than them in reprospective group.The morbidity of VAP,reintubation rates and mortality of patients in prospective group were lower than another.The extubation successful rates of patients received NIPPV sequential treatment was significant higher than patients with no received NIPPV sequential treatment.Conclusion:The successful rate for patients with AECOPD in weaning of IPPV would be improved significantly by sequential treatment of NIPPV.The time of SBTs should not be lasted more than 120 minutes." @default.
• W2373752190 created "2016-06-24" @default.
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• W2373752190 date "2009-01-01" @default.
• W2373752190 modified "2023-09-25" @default.
• W2373752190 title "Evaluation of Noninvasive Positive Pressure Ventilation in Weaning of Invasive Positive Pressure Ventilation for Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease" @default.
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