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- W2373776983 abstract "Objective To investigate the relationship between serum levels of insulin-like growth factor-1 (IGF-I) and male elderly osteoporosis. Methods Serum IGF-I levels and other biochemical parameters were measured in 26 old male osteoporotic patients and 28 male controls. Meanwhile, bone mineral density (BMD) was also determined. Results The BMD of lumbar spine and left femeral neck in elderly osteoporotic group was much lower than that in control group. And levels of IGF-I were significantly lower than those in controls(80.40 ± 17.41) ng/mLand (157.82 ± 28.80) ng/mL respectively (P 0.001). There were no statistically significant differences in the serum contents of calcium, phosphorus and alkaline phosphatase (ALP) between the two groups. In both control and osteoporotic group, the BMD of lumbar spine or left femoral neck was positively related to the serum levels of IGF-I (control group: r = 0.455, P0.05; r = 0.493, P 0.01;osteoporotic group: r = 0.529, P 0.01; r = 0.657, P 0.01), and had no relationship with levels of serum calcium, phosphorus and ALP. Conclusion Serum IGF-I levels are positively correlated with BMD, and IGF-I can be a good indicator for diagnosing male elderly osteoporosis." @default.
- W2373776983 created "2016-06-24" @default.
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- W2373776983 date "2004-01-01" @default.
- W2373776983 modified "2023-09-25" @default.
- W2373776983 title "Clinical significance of serum insulin-like growth factor-Ilevels in male elderly osteoporosis" @default.
- W2373776983 hasPublicationYear "2004" @default.
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