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- W2373797113 abstract "We studied the effects of salvianolic acid B(Sa1.B)、Rb、Re and Rg fractions of Danshen or Sanqi on platelet aggregation and adhesion,TXA 2 and PGI 2 in normal rats. The results demonstrated that Re fraction (68mg/kg)and Rg fraction (108mg/kg),given orally,could markedly counteract ADP induced platelet aggregation.Rg fraction (108mg/kg) and Sal.B fraction(48mg/kg) could markedly inhibit platelet adhesion.Rb fraction(112mg/kg) have no effects on platelet aggregation and on adhesion.Rg fraction(108mg/kg) and Sal.B fraction (48mg/kg) could markedly decrease the level of TXA 2,but had little effect on 6 Keto PGF 1α . Moreover, Rg fraction 108mg/kg could decrease the ration of TXB 2/6 Keto PGF 1α ,too. The results suggested that the inhibition effects on platelet aggregation and adhesion of Rg fraction(108mg/kg) and Sal.B fraction(48mg/kg) of Danshen or Sanqi might be closely related to its inhibition effect on the release of TXA 2 in normal rats." @default.
- W2373797113 created "2016-06-24" @default.
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- W2373797113 date "2004-01-01" @default.
- W2373797113 modified "2023-09-25" @default.
- W2373797113 title "Effects of Active Fractions of Danshen or Sanqi on Platelet Adhesion,Aggregation and TXA_2,PGI_2 in Normal Rats" @default.
- W2373797113 hasPublicationYear "2004" @default.
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