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- W2373809807 abstract "Objective] To study soluble human leukocyte antigen G(sHLA G) expression of cleavage stage embryo and the relationship between SHLA G embryo development or implantation by detecting the quality and quantity of sHLA G in their culture medium. The expression of sHLA G and other sHLA I antigens were detected by Immunofluorescence Western Blot. sHLA I levels were measured in each embryo's culture medium by ELISA and the relationships between sHLA I antigens and embryo development and implantation of cleavage stage embryo were analyzed. ① Western blot analysis showed dominant expression of soluble HLA G antigen. Other soluble HLA I antigens were not detected by the same method. Therefore the level of HLA I in culture medium was close to the level of HLA G. ② The value of soluble HLA I or sHLA G secreted from the first class cleavage stage embryos was 0.077± 0.006, the second class embryo was 0.064± 0.002, the third class embryo was 0.043± 0.002, and there were significant differences in the three groups (P=0.014). Correlation coefficient of the A value of sHLA I and embryo implantation rate was 0.426, P=0.004. So the soluble HLA I or sHLA G secreted from the cleavage stage embryos was related to embryo implantation rate and embryo quality. [ Conclusion] sHLA G expression is closely related to embryo development and implantation of cleavage stage embryo." @default.
- W2373809807 created "2016-06-24" @default.
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- W2373809807 date "2003-01-01" @default.
- W2373809807 modified "2023-09-25" @default.
- W2373809807 title "The Relationship Between sHLA-G Expression of Cleavage Stage Embryo and Embryo Development" @default.
- W2373809807 hasPublicationYear "2003" @default.
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