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- W2373816650 abstract "Objective To investigate the effect of aspirin on the incidence of thromboembolism in hypertensive patients associated with paroxysmal atrial fibrillation.MethodsFour hundred hypertensive patients with paroxysmal atrial fibrillation (mean age 59 years) free of thromboembolic events were randomized assigned to receive aspirin (0.3 g/d) or placebo. Cerebral thromboembolism,including transient ischemic attack and embolism of peripheral arteries were defined as primary outcomes. Event-free survival curves were estimated by Kaplan-Meier curve. Results During 3.6 years follow-up,primary outcomes occurred in 61 patients (4.3% per year). Aspirin significantly reduced the incidence of primary outcome as compared with placebo group( 9.0% vs 21.5%,P0.001). Kaplan-Meier curve also showed greater free thromboembolism rate in the aspirin treatment group(υ= 1,P=0.0004). Conclusion Aspirin significantly prevents the risks for thromboembolism in hypertensive patients associated with paroxysmal atrial fibrillation." @default.
- W2373816650 created "2016-06-24" @default.
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- W2373816650 date "2006-01-01" @default.
- W2373816650 modified "2023-09-28" @default.
- W2373816650 title "Effect of Aspirin on Thromboembolism in Hypertensive Patients Associated with Paroxysmal Atrial Fibrillation" @default.
- W2373816650 hasPublicationYear "2006" @default.
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