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- W2373858589 abstract "Objective To describe the clinical and imaging features of peripheral primitive neuroectodermal tumors (pPNETs) of the bone.Methods The clinical data, plain films, and CT and MR images in 10 patients with pathologically proved pPNETs were reviewed retrospectively.Results The age at diagnosis ranged from 8 years to 68 years (mean 24.4 years). The clinical presentations of most cases were local pain (9/10) with a mass grew quickly (7/10). The X-ray findings were lytic lesion (8 cases), lytic lesion with irregular sclerosis and dilation (1 case), and normal (1 case). Soft tissue mass was present in 7 cases. No case had periosteal reaction. CT scan was performed in 7 cases, and the CT findings included lytic lesion (6 cases), lytic lesion with irregular sclerosis and dilation (1 case), soft tissue mass (7 cases), speculate calcification (2 cases), and no periosteal reaction. MRI was conducted in 10 cases. Isointensity (9 cases) and slight hyperintensity (1 case) were demonstrated on T 1WI, and heterogeneous iso- or hyperintensity (8 cases) and homogeneous hyperintensity (2 cases) on T 2WI and STIR images. Large mass was detected in all the cases. In 5 cases with contrast enhancement, moderate enhancement was present in 2 cases, and marked heterogeneous enhancement in 3 cases. After 4 courses of chemotherapy in 4 cases, the size of the lesions decreased markedly.Conclusion Most cases of pPNETs were in patients under 30 years, the clinical presentations were local pain with a mass that grows quickly. The imaging features of pPNETs were a destructive lesion with a massive soft tissue mass without periosteal reaction. The imaging is useful in delineating the extent of tumor and monitoring treatment, although the imaging findings are nonspecific." @default.
- W2373858589 created "2016-06-24" @default.
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- W2373858589 date "2004-01-01" @default.
- W2373858589 modified "2023-09-24" @default.
- W2373858589 title "Imaging features of peripheral primitive neuroectodermal tumors of the bone" @default.
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