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- W2373944462 abstract "OBJECTIVE To study the therapeutic effects of DanHong injection on vascular dementia mice and its mechanism.METHODS Male SD rats were randomly allocated into sham operation group(SO),operation group(PO),DanHong treatment group(DHT),Morris water maze test was performed.Concentrations of malondialdehyde,glutamic acid and GSH-PX activity of cerebral tissue of different groups rats were determined at the end of experiment.RESULTS The average escape latency of PO rats was significantly longer than the other groups during platform orientation test(P0.05),the probe time of the PO group was much shorter than SO during spatial probe test(P0.01).Malondialdehyde,glutamic acid concentrations of cerebral tissue of PO were significant higher than those of SO,DHT(P0.01).The GSHPX activity of PO was much lower than that of SO,DHT(P0.01).CONCLUSION DanHong injection could treat vascular dementia by inhibiting lipid peroxidation reaction and release of excitatory amino acids and protecting enzymatic activity." @default.
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- W2373944462 date "2008-01-01" @default.
- W2373944462 modified "2023-09-28" @default.
- W2373944462 title "Influence of DanHong injection on malondialdehyde,glutamic acid and GSH-PX of cerebral tissue in chronic cerebral ischemia mice" @default.
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