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- W2373950612 abstract "Objective To investigate the practical significance of less intense and lower cost protocol to cure children with non-high-risk acute lymphoblastic leukemia(ALL)in developing countries such as in China.Methods Under the circumstances of informed consent,parents of 52 children(40 males,12 femalse,aged from 1 to 14 years old) with newly diagnosed ALL from May 1999 to Sep.2006,decided whether to accept less intense and lower cost protocol for the treatment of their children.The long term treatment outcome of the protocol was estimated by the method Kaplan-Meier,and the data of hospitalization cost was obtained from the case record department.Results Children accepted the protocol from low income families.Three children failed to induce.Two of them were non-remission,the other one gave up the treatment when the course of treatment was not over.The complete remission rate was 94.2%.For the patients with non-high-risk ALL,the 4 years and 7 years possibility event-free survi-val(pEFS) were 72.8% and 67.2%,4 years and 7 years possibility disease-free survival(pDFS) were 74.3% and 68.6%,respectively.The median impatient chemotherapy cost was 32 000 yuan(23 000-51 000 yuan).Conclusions This trial shows that less intense protocol appears to achieve a reasonable EFS and DFS for childhood non-high-risk ALL with a much lower cost.This will be especially important in areas with low family income." @default.
- W2373950612 created "2016-06-24" @default.
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- W2373950612 date "2008-01-01" @default.
- W2373950612 modified "2023-09-24" @default.
- W2373950612 title "Less Intense and Lower Cost Protocol for Children with Non-High-Risk Acute Lymphoblastic Leukemia" @default.
- W2373950612 hasPublicationYear "2008" @default.
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