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- W2373968769 abstract "Objective To study the relationship between serum levels of retinol binging protein 4( RBP4) and insulin resistance,pancreaticβ-cell function in newly diagnosed type 2 diabetic patients. Methods 31 normal weight DM subjects( BMI 25,20 men,11women),32 obese DM subjects( BMI≥25,22 men,10women) and 50 normal subjects( 28 men,22women) were randomly selected. The serum RBP4 levels were measured by enzyme-linked immunosorbent assay. The fast glucose( FPG),total-serum cholesterol( TC),fasting insulin( FINS),triglyceride( TG) were measured. The body height,weight and blood pressure were measured. At the same time,the HOMA-IR,HOMA-B,BF%,MBCI,BMI and WHR were calculated. Results The serum RBP4 were much higher in obese DM subjects than were in non-obese DM subjects and the control group. The difference was significant( P 0. 05). The serum RBP4 levels were higher in obese DM subjects than that in the non-obese DM subjects( P 0. 05),and the serum RBP4 level showed positive correlation with BMI,BF%,WHR,MBCI,HOMA-IR. The multiple regression analysis showed the serum level of RBP4 was positively correlated to insulin resistance. Conlusion The insulin resistance are higher in obese diabetes mellitus patients. RBP4 is positively correlated to insulin resistance and beta cell function." @default.
- W2373968769 created "2016-06-24" @default.
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- W2373968769 date "2014-01-01" @default.
- W2373968769 modified "2023-09-23" @default.
- W2373968769 title "The correlation of levels of serum RBP4 with insulin resistance and pancreaticβ-cell function in newly diagnosed type 2 diabetic patients" @default.
- W2373968769 hasPublicationYear "2014" @default.
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