Matches in SemOpenAlex for { <https://semopenalex.org/work/W2373982485> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2373982485 abstract "The interaction between urea and bovine hemoglobin (BHb) in aqueous solution as well as the denaturation process of BHb were studied by using isothermal microcalorimetry method and equilibrium dialysis technique at 30 ℃ and three pHs.The average binding numbers,the values of binding enthalpy of urea to BHb and the values of enthalpy per mole of urea were obtained.The simple binding model was employed to obtain the binding constant and the binding free energies.The results which were obtained by thermodynamic analysis indicated that the denaturation of BHb induced by urea is through direct and indirect effects,the interaction between urea and BHb is divided into three stages:the first stage is at the urea concentration below 4 mol L-1.In this stage,the direct interaction between urea and BHb is the main interaction,while the direct interaction is stronger under acidulous condition.The second stage is in the urea concentrations from 4 mol L-1 to 6 mol L-1.In this stage,the structure of the water around the BHb is changed by the interaction of urea and solvent water.When the urea concentration reaches 6mol L-1,the two interactions together cause the structural damage of the BHb and expose the groups which are in the inner structure of BHb.The third stage is at the urea concentrations higher than 6 mol L-1.In this stage,urea molecules combine with the exposed groups.The destruction of the structure of BHb is not a gradual process,but rather a completely destruction at once and the thermal effect resulting from the structural damage is not too much." @default.
- W2373982485 created "2016-06-24" @default.
- W2373982485 creator A5050707734 @default.
- W2373982485 date "2010-01-01" @default.
- W2373982485 modified "2023-09-22" @default.
- W2373982485 title "Denaturation study of bovine hemoglobin induced by the urea by microcalorimetry and equilibrium dialysis" @default.
- W2373982485 hasPublicationYear "2010" @default.
- W2373982485 type Work @default.
- W2373982485 sameAs 2373982485 @default.
- W2373982485 citedByCount "0" @default.
- W2373982485 crossrefType "journal-article" @default.
- W2373982485 hasAuthorship W2373982485A5050707734 @default.
- W2373982485 hasConcept C121332964 @default.
- W2373982485 hasConcept C13965031 @default.
- W2373982485 hasConcept C147789679 @default.
- W2373982485 hasConcept C178790620 @default.
- W2373982485 hasConcept C184651966 @default.
- W2373982485 hasConcept C185592680 @default.
- W2373982485 hasConcept C2776923230 @default.
- W2373982485 hasConcept C2780365088 @default.
- W2373982485 hasConcept C2780471494 @default.
- W2373982485 hasConcept C3288061 @default.
- W2373982485 hasConcept C32909587 @default.
- W2373982485 hasConcept C43617362 @default.
- W2373982485 hasConcept C45902088 @default.
- W2373982485 hasConcept C8010536 @default.
- W2373982485 hasConcept C97355855 @default.
- W2373982485 hasConceptScore W2373982485C121332964 @default.
- W2373982485 hasConceptScore W2373982485C13965031 @default.
- W2373982485 hasConceptScore W2373982485C147789679 @default.
- W2373982485 hasConceptScore W2373982485C178790620 @default.
- W2373982485 hasConceptScore W2373982485C184651966 @default.
- W2373982485 hasConceptScore W2373982485C185592680 @default.
- W2373982485 hasConceptScore W2373982485C2776923230 @default.
- W2373982485 hasConceptScore W2373982485C2780365088 @default.
- W2373982485 hasConceptScore W2373982485C2780471494 @default.
- W2373982485 hasConceptScore W2373982485C3288061 @default.
- W2373982485 hasConceptScore W2373982485C32909587 @default.
- W2373982485 hasConceptScore W2373982485C43617362 @default.
- W2373982485 hasConceptScore W2373982485C45902088 @default.
- W2373982485 hasConceptScore W2373982485C8010536 @default.
- W2373982485 hasConceptScore W2373982485C97355855 @default.
- W2373982485 hasLocation W23739824851 @default.
- W2373982485 hasOpenAccess W2373982485 @default.
- W2373982485 hasPrimaryLocation W23739824851 @default.
- W2373982485 hasRelatedWork W1569015250 @default.
- W2373982485 hasRelatedWork W1586605199 @default.
- W2373982485 hasRelatedWork W1617935550 @default.
- W2373982485 hasRelatedWork W1856552113 @default.
- W2373982485 hasRelatedWork W1974822254 @default.
- W2373982485 hasRelatedWork W1981583379 @default.
- W2373982485 hasRelatedWork W2006745333 @default.
- W2373982485 hasRelatedWork W2015461118 @default.
- W2373982485 hasRelatedWork W2021080677 @default.
- W2373982485 hasRelatedWork W2025902586 @default.
- W2373982485 hasRelatedWork W2028852382 @default.
- W2373982485 hasRelatedWork W2047222693 @default.
- W2373982485 hasRelatedWork W2049385819 @default.
- W2373982485 hasRelatedWork W2075100950 @default.
- W2373982485 hasRelatedWork W2076828221 @default.
- W2373982485 hasRelatedWork W2082849164 @default.
- W2373982485 hasRelatedWork W2415157217 @default.
- W2373982485 hasRelatedWork W2416224306 @default.
- W2373982485 hasRelatedWork W2978484296 @default.
- W2373982485 hasRelatedWork W3139694339 @default.
- W2373982485 isParatext "false" @default.
- W2373982485 isRetracted "false" @default.
- W2373982485 magId "2373982485" @default.
- W2373982485 workType "article" @default.