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- W2373996831 abstract "Lornoxicam was synthesized from methyl 5-chloro-3-sulfamoylthiophene-2-carboxylate in five steps,the effect of temperature on each reaction was investigated.The results demonstrated that temperature had significant effect on product yield in each step.The optimum temperatures of five-stage reactions were 25 ℃,130—135 ℃,30 ℃,25 ℃ and 190—194 ℃,respectively.The total yield of lornoxicam was 17 % under these conditions.This process has obvious advantages such as simplicity,safety,easy control,less side-reactions,high yield and low cost." @default.
- W2373996831 created "2016-06-24" @default.
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- W2373996831 date "2012-01-01" @default.
- W2373996831 modified "2023-09-26" @default.
- W2373996831 title "Synthesis of Lornoxicam and Temperature Optimization" @default.
- W2373996831 hasPublicationYear "2012" @default.
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