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- W2374001805 abstract "OBJECTIVE To prepare the preparation of compound Huangqin temperature sensitive gel,and to establish the quality control standard to determine the content of baicalin temperature sensitive gel. METHODS Bo Losham was choosed as gel material,the influence of different concentration ratio of Bo Losham 407(Pluronic F127)and Bo Losham 188(Pluronic F68) on the prescription on the gel temperature was investigatal. HPLC method was established for determination of Baicalin in gel: the chromatographic column was Acclaim 120 C18column(4. 6mm ×250mm,5μm); the mobile phase of methanol water phosphoric acid(57∶ 43∶ 0. 2),the flow rate was 1. 0m L·min- 1;the detection wavelength was 280 nm and the column temperature was 30℃. RESULTS The gelation temperature was 29. 5℃ gel matrix: 22% P407 /8% P188. Baicalin in 0. 0253 ~ 0. 1508(mg·m L- 1) the linear relationship is good,the average recovery was 103. 74%,RSD was 1. 26%. CONCLUSION The poloxamer temperature sensitive gel preparation process is simple,the prescription screening gelobtained is suitable for clinical skin medication. The quality standard is accurate,reliable,reproducible and can be used for quality control of compound Huangqin temperature sensitive gel." @default.
- W2374001805 created "2016-06-24" @default.
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- W2374001805 date "2014-01-01" @default.
- W2374001805 modified "2023-09-25" @default.
- W2374001805 title "Studies on the Preparation and Quality Standard of Compound Huangqin Temperature Sensitive gel" @default.
- W2374001805 hasPublicationYear "2014" @default.
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