FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2374004474> ?p ?o ?g. }

• W2374004474 abstract "Objective To investigate the curative effects and complications of microwave ablation in the treatment of conventional osteosarcoma in the femur and tibia.Methods From September 2006 to June 2010,15 patients were adopted,including 9 males and 6 females with a median age of 16 years old(range;5-52 years).The locational distribution was stated as following.There were 6 cases in the distal femur,5 cases in the femoral diaphysis and the other 4 cases in the proximal tibia.All the patients were classified as stage Ⅱ B according to the Enneking staging system.After the diagnosis was confirmed by biopsy in all the patients,the combined chemotherapy was performed for 1 cycle before the surgery.The tumors were exposed according to the principle of wide resection of malignant tumors.The matrix microwave ablation with several antennas was performed on the tumor-bearing bone.The necrotic tumor tissues were removed after the ablation.The autogeneic or allogeneie fibular grafting and plate fixation were performed in 5 cases.The bone cementation and plate fixation were performed in 3 cases.The autogeneic or allogeneic fibular grafting and plate fixation combined with bone cementation were performed in 2 cases.The simple plate fixation was performed in 3 cases.The simple intramedullary nail fixation was performed in 2 cases.Postoperatively the adjuvant chemotherapy was performed for 4 cycles after the preoperative chemotherapy.During the follow-up,the patients were reexamined at each 3 months during the first 2 years,and later at each 6 months.From the 5th year after the operation,reexamination was performed once 1 year until December 2013.Results All the patients were followed up for 51±20 months.Postoperatively 4 patients had recurrence and lung metastases with the mean recurrence time of 10.2months and 1 patient had simple lung metastases,who all died.The other 10 patients remained cancer-free.The recurrence rate was 26.7% .The recurrence occurred in the bone in 3 cases,and in the soft tissues in 1 case.The rate of lung metastases was 33.3% .The 2-year and 5-year overall survival rates were 73% and 53% respectively.Pathological fractures and breakage of internal fixation occurred in 6 cases,and the fracture rate was 40% .The flexion and extension functions of the knee joints were evaluated at 6 months after the operation,which were close to normal.While in the long-term follow-up,the limb functions of the patients with pathological fi'actures were obviously aggravated.The scores of the patients with pathological fractures were obviously lower than that of the patients without fractures at 3 years after the operation,and the differences were statistically significant(P0.01).Conclusions Because there are limited cases in this study,it is hard to draw a definite conclusion.However,there are some beneficial prompts.For the patients with osteosarcoma in the long bones of the lower extremity,the overall survival rate of microwave ablation is comparable to that of other treatment methods in our country.While the technique should be further improved to make sure that the tumors are completely inactivated,so as to reduce the local recurrence.In addition,a long period is needed in the inactivation and recovery process and a high risk of pathological fractures exists after the bone grafting and internal fixation,so a firmer reconstruction method should be adopted.In the treatment of osteosarcoma in the joints of the lower extremity,the tumor wide resection and artificiaI joint replacement maybe an ideal choice." @default.
• W2374004474 created "2016-06-24" @default.
• W2374004474 creator A5036067695 @default.
• W2374004474 date "2014-01-01" @default.
• W2374004474 modified "2023-09-25" @default.
• W2374004474 title "Microwave ablation for osteosarcoma in the long bones of the lower extremity:15 cases report" @default.
• W2374004474 hasPublicationYear "2014" @default.
• W2374004474 type Work @default.
• W2374004474 sameAs 2374004474 @default.
• W2374004474 citedByCount "0" @default.
• W2374004474 crossrefType "journal-article" @default.
• W2374004474 hasAuthorship W2374004474A5036067695 @default.
• W2374004474 hasConcept C141071460 @default.
• W2374004474 hasConcept C142724271 @default.
• W2374004474 hasConcept C146249460 @default.
• W2374004474 hasConcept C2776337968 @default.
• W2374004474 hasConcept C2777236700 @default.
• W2374004474 hasConcept C2777760704 @default.
• W2374004474 hasConcept C2780554211 @default.
• W2374004474 hasConcept C2908647359 @default.
• W2374004474 hasConcept C71924100 @default.
• W2374004474 hasConcept C92162645 @default.
• W2374004474 hasConcept C99454951 @default.
• W2374004474 hasConceptScore W2374004474C141071460 @default.
• W2374004474 hasConceptScore W2374004474C142724271 @default.
• W2374004474 hasConceptScore W2374004474C146249460 @default.
• W2374004474 hasConceptScore W2374004474C2776337968 @default.
• W2374004474 hasConceptScore W2374004474C2777236700 @default.
• W2374004474 hasConceptScore W2374004474C2777760704 @default.
• W2374004474 hasConceptScore W2374004474C2780554211 @default.
• W2374004474 hasConceptScore W2374004474C2908647359 @default.
• W2374004474 hasConceptScore W2374004474C71924100 @default.
• W2374004474 hasConceptScore W2374004474C92162645 @default.
• W2374004474 hasConceptScore W2374004474C99454951 @default.
• W2374004474 hasLocation W23740044741 @default.
• W2374004474 hasOpenAccess W2374004474 @default.
• W2374004474 hasPrimaryLocation W23740044741 @default.
• W2374004474 hasRelatedWork W2029579737 @default.
• W2374004474 hasRelatedWork W2094890392 @default.
• W2374004474 hasRelatedWork W2348335392 @default.
• W2374004474 hasRelatedWork W2385503815 @default.
• W2374004474 hasRelatedWork W2387672883 @default.
• W2374004474 hasRelatedWork W2399914269 @default.
• W2374004474 hasRelatedWork W2408981039 @default.
• W2374004474 hasRelatedWork W2416346711 @default.
• W2374004474 hasRelatedWork W2473830138 @default.
• W2374004474 hasRelatedWork W2505636999 @default.
• W2374004474 hasRelatedWork W2524427804 @default.
• W2374004474 hasRelatedWork W2531804082 @default.
• W2374004474 hasRelatedWork W2566312924 @default.
• W2374004474 hasRelatedWork W3025527574 @default.
• W2374004474 hasRelatedWork W3029429632 @default.
• W2374004474 hasRelatedWork W3029657503 @default.
• W2374004474 hasRelatedWork W3030798181 @default.
• W2374004474 hasRelatedWork W3031869116 @default.
• W2374004474 hasRelatedWork W3149298112 @default.
• W2374004474 hasRelatedWork W335727258 @default.
• W2374004474 isParatext "false" @default.
• W2374004474 isRetracted "false" @default.
• W2374004474 magId "2374004474" @default.
• W2374004474 workType "article" @default.