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- W2374005855 abstract "Aim:To study the expression levels of tetraspanin-1(TSPAN-1) and Ki-67,and their relationship in cervical cancer.Methods:The expression levels of TSPAN-1 and Ki-67 proteins in normal cervix tissue,cervical cancer tissue and cervical intraepithelial neoplasia tissue (CIN) (each n=30) were detected by the immunohistochemical SP method.Results:The positive expression rate of TSPAN-1 and Ki-67 were 0,36.7%,7.33%,and 13.3%,53.3%,80.0% in the three groups,and there were obvious differences(χ2=34.737 and 27.036,P0.001).The expression of TSPAN-1 and Ki-67 proteins increased progressively from normal cervix to CIN and to cervical carcinoma(P0.05).The expression of TSPAN-1 was related to the lymph node metastasis status (P=0.014).In cervical carcinoma,the expression levels of TSPAN-1 and Ki-67 were associated (χ2=8.960,rp=0.539,P0.001).Conclusion:The overexpression of TSPAN-1 is closely related to the proliferation and contribute to the oncogenesis of cervical cancer." @default.
- W2374005855 created "2016-06-24" @default.
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- W2374005855 date "2010-01-01" @default.
- W2374005855 modified "2023-09-26" @default.
- W2374005855 title "Expression of TSPAN-1 and Ki-67 proteins in cervical carcinoma tissue" @default.
- W2374005855 hasPublicationYear "2010" @default.
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