Matches in SemOpenAlex for { <https://semopenalex.org/work/W2374023667> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2374023667 abstract "Objective To investigate the effect of Danggui Beimu Kushen pill(angelica, fritillaria, sophorae) on the pathological morphology of tumor, liver, kidney and thymus of cisplatin-treated H22 tumor-bearing mice, and explore its effect-enhancing and toxic-reducing action for cisplatin. Methods H22 tumor-bearing mice models were established, and randomized into model group, cisplatin group, Danggui Beimu Kushen pill group, Danggui Beimu Kushen pill combined cisplatin group, with normal group as control. Drugs were administrated from the eighth day for 14 d, the tumor volume of tumor-bearing mice was dynamically monitored. On the 15th days, the mice were killed to observe the pathological changes of tumor, liver, kidney and thymus under the microscope. Results After treatment for 10 d, compared with model group, the tumor volume of each treatment group was significantly decreased(P 0.01), Danggui Beimu Kushen pill group was most obvious. Compared with model group, the tumor cellularities, atypia and irregular mitosis of each treatment group were significantly decreased(P 0.01), the effect of Danggui Beimu Kushen pill combined cisplatin group was better than that of cisplatin group, accompanied by obvious lymphocyte infiltration and hyperplasia of fibrous tissue(P 0.01). The pathomorphological damages of liver, kidney and thymus in cisplatin group were obviously aggravating than normal group and model group(P 0.01), however the degree of damages in Danggui Beimu Kushen pill combined cisplatin group were reduced(P 0.05). Conclusion Danggui Beimu Kushen pill can not only enhance the antitumor effect of cisplatin, but also reduce cisplatin toxicity to liver, kidney and thymus of H22 tumor-bearing mice." @default.
- W2374023667 created "2016-06-24" @default.
- W2374023667 creator A5029337331 @default.
- W2374023667 date "2014-01-01" @default.
- W2374023667 modified "2023-09-22" @default.
- W2374023667 title "Effect of Danggui Beimu Kushen Pill on Pathological Morphology of Tumor, Liver, Kidney and Thymus of H22 Tumor-bearing Mice Treated with Cisplatin" @default.
- W2374023667 hasPublicationYear "2014" @default.
- W2374023667 type Work @default.
- W2374023667 sameAs 2374023667 @default.
- W2374023667 citedByCount "0" @default.
- W2374023667 crossrefType "journal-article" @default.
- W2374023667 hasAuthorship W2374023667A5029337331 @default.
- W2374023667 hasConcept C126322002 @default.
- W2374023667 hasConcept C207886595 @default.
- W2374023667 hasConcept C2776694085 @default.
- W2374023667 hasConcept C2777562237 @default.
- W2374023667 hasConcept C2778239845 @default.
- W2374023667 hasConcept C2780091579 @default.
- W2374023667 hasConcept C556039675 @default.
- W2374023667 hasConcept C71924100 @default.
- W2374023667 hasConcept C81603835 @default.
- W2374023667 hasConcept C90924648 @default.
- W2374023667 hasConcept C98274493 @default.
- W2374023667 hasConceptScore W2374023667C126322002 @default.
- W2374023667 hasConceptScore W2374023667C207886595 @default.
- W2374023667 hasConceptScore W2374023667C2776694085 @default.
- W2374023667 hasConceptScore W2374023667C2777562237 @default.
- W2374023667 hasConceptScore W2374023667C2778239845 @default.
- W2374023667 hasConceptScore W2374023667C2780091579 @default.
- W2374023667 hasConceptScore W2374023667C556039675 @default.
- W2374023667 hasConceptScore W2374023667C71924100 @default.
- W2374023667 hasConceptScore W2374023667C81603835 @default.
- W2374023667 hasConceptScore W2374023667C90924648 @default.
- W2374023667 hasConceptScore W2374023667C98274493 @default.
- W2374023667 hasLocation W23740236671 @default.
- W2374023667 hasOpenAccess W2374023667 @default.
- W2374023667 hasPrimaryLocation W23740236671 @default.
- W2374023667 hasRelatedWork W2351293207 @default.
- W2374023667 hasRelatedWork W2355922365 @default.
- W2374023667 hasRelatedWork W2357154559 @default.
- W2374023667 hasRelatedWork W2360023992 @default.
- W2374023667 hasRelatedWork W2363506929 @default.
- W2374023667 hasRelatedWork W2367521253 @default.
- W2374023667 hasRelatedWork W2369782838 @default.
- W2374023667 hasRelatedWork W2370662823 @default.
- W2374023667 hasRelatedWork W2379099095 @default.
- W2374023667 hasRelatedWork W2379548607 @default.
- W2374023667 hasRelatedWork W2379809341 @default.
- W2374023667 hasRelatedWork W2384859174 @default.
- W2374023667 hasRelatedWork W2385947499 @default.
- W2374023667 hasRelatedWork W2387891237 @default.
- W2374023667 hasRelatedWork W2393584324 @default.
- W2374023667 hasRelatedWork W2394353497 @default.
- W2374023667 hasRelatedWork W2751500819 @default.
- W2374023667 hasRelatedWork W279336614 @default.
- W2374023667 hasRelatedWork W2949798357 @default.
- W2374023667 hasRelatedWork W3029368641 @default.
- W2374023667 isParatext "false" @default.
- W2374023667 isRetracted "false" @default.
- W2374023667 magId "2374023667" @default.
- W2374023667 workType "article" @default.