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- W2374038898 abstract "Objective: To study the abnormal expressions of tumor suppressor nm23 and p53 protein in cervical cancer, and their relationships with tumor biological characteristics including clinical stages, pathological grades and lymph node metastasis and so on. Methods: Immunohistochemical technique was used to examine the expression of nm23 and p53 in 60 cases of cervical squamous cell carcinoma and 15 cases of normal cervical tissues. Results: The expression of nm23 showed significant difference in tumor grades, clinical stages and local lymph node metastasis compared with p53, and they were negatively correlated. Conclusion: nm23 and p53 protein may play an important role in the development of cervical carcinoma, they promote mutually especially in tumor invasion and metastasis. The combined detection of the expression of nm23 and p53 protein can be used to estimate metastatic potentiality and predict the accuracy of clinical treatment." @default.
- W2374038898 created "2016-06-24" @default.
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- W2374038898 date "2009-01-01" @default.
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- W2374038898 title "Expression and significance of nm23 and p53 in cervical cancer" @default.
- W2374038898 hasPublicationYear "2009" @default.
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