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- W2374057963 abstract "OBJECTIVE:The pharmaceutics of Amikacin(AMK)in old patients with respiratory system infections was studied to provide a basis for clinical use.METHODS:Fluorescence polarizing immunoassay method was employed to detect blood drug concentration.RESULTS:The blood concentration-time curve of AMK fitted in with the two-compartment modˉel.The T 1/2β and AUC of AMK in the healthy volunteers and old patients with respiratory system infections were(2.14±0.81)h and(4.32±1.05)h(P0.01),and(70.68±26.47)(mg·h)/L and(101.83±9.73)(mg·h)/L respectively(P0.01).CONCLU SION:The pharmacokinetic process of AMK in the old patients with respiratory system infections is obviously different from that in the healthy volunteers." @default.
- W2374057963 created "2016-06-24" @default.
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- W2374057963 date "2004-01-01" @default.
- W2374057963 modified "2023-09-25" @default.
- W2374057963 title "The Pharmacokinetics Study of Amikacin in Old Patients with Respiratory System Infections" @default.
- W2374057963 hasPublicationYear "2004" @default.
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