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- W2374072997 abstract "Objective To preliminarily study the analgesic and anti-inflammatory effects of extracts of Chinese drug Great Burdock Achene.Methods A simple water extract and a alcohol extract of Great Burdock Achene were used in this study.Acetic acid-induced twisting test and hot plate test were performed for evaluating analgesic effects of Great Burdock Achene on mouse.Auricle swelling induced by xylene test and pedal swelling induced by 10% albumen test were performed for evaluating anti-inflammatory effects of Great Burdock Achene on mice. Results Water extract and alcohol extract of Great Burdock Achene could inhibit twisting times in mice induced by acetic acid.During the hot plate test, water extract and alcohol extract of Great Burdock Achene could elevate the threshold of pain in mice at 0.5h,1 h and 1.5 h after the mice receiving drugs,respectively.Alcohol extract of Great Burdock Achene could obviously alleviate mouse auricle swelling induced by xylene.At 0.5 h,1 h,2 h and 4 h after the pedal swelling induced by 10% albumen,water extract and alcohol extract of Great Burdock Achene could also inhibit pedal swelling.Conclusion Traditional Chinese drug Great Burdock Achene can have certain analgesic and anti-inflammatory effects." @default.
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- W2374072997 date "2012-01-01" @default.
- W2374072997 modified "2023-09-28" @default.
- W2374072997 title "An experimental study of the analgesic and anti-inflammatory effects of extracts of Great Burdock Achene on mice" @default.
- W2374072997 hasPublicationYear "2012" @default.
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