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- W2374078182 abstract "Objective: To investigate the mechanism of triptolide on proliferation inhibition of bovine lens epithelial cell (BLECs) in vitro. Methods: The fourth generation of BLECs were used to investigate the effects of Triptolide on proliferation inhibitory rate at the concentrations of 20 μg/L,for 6,12,24,48,72 hours respectively by MTT colorimetry assay. The cytoplasmic free Ca2+ was measured with Fura-2 fluorescence determination and by radioimmunoassay methods. Results: The same concentrations of Triptolide produced effectively inhibition for proliferation of BLECs in different times and the inhibition rates found by the time-dependent way. The levels of intracellular Ca2+ were obviously higher in the tissues of inhibitory proliferation. Conclusion: Triptolide could effectively inhibit the proliferation of BLECs in vitro. One of the mechanisms of Triptolide on proliferation is by means of cytoplasmic free Ca2+." @default.
- W2374078182 created "2016-06-24" @default.
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- W2374078182 date "2005-01-01" @default.
- W2374078182 modified "2023-09-27" @default.
- W2374078182 title "EFFECTS OF TRIPTOLIDE ON BOTH INTRACELLULAR Ca~(2+) CONCENTRATION AND PROLIFERATING OF CULTURED BOVINE LENS EPITHELIAL CELLS" @default.
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