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- W2374099027 abstract "ObjectiveTo investigate the therapeutic effect of traditional Chinese prescription Shenlingbaizhu Extract on radiation-induced intestinal injury in mice.MethodsProliferation improvement of irradiated intestinal epithelial cells(IEC-6) was tested by MTT assay in vitro.The preventive effect of the prescription was also tested in vivo.Mice were treated with Shenlingbaizhu by intragastric administration immediately after receiving local irradiation to the abdomen at a dose of 10 Gy(60Co γ-ray).The body mass,diarrhea and survival were recorded.The pathological changes in the jejunum of mice were stained by HE and observed.ResultsShenlingbaizhu Extract could significantly promote the proliferation of irradiated intestinal epithelial cells in vitro.Shenlingbaizhu Extract treatment reduced the diarrhea of irradiated mice,improved the intestinal structural recovery and increased the mice survival.ConclusionTraditional Chinese prescription Shenlingbaizhu Extract shows significant protective effect on radiation-induced intestinal injury in mice,providing data for clinical treatment of radiation-induced intestinal injury." @default.
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- W2374099027 date "2011-01-01" @default.
- W2374099027 modified "2023-09-28" @default.
- W2374099027 title "Chinese prescription Shenlingbaizhu Extract prevents radiation-induced small intestinal injury in mice" @default.
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