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- W2374103634 abstract "Objective To investigate the distribution features and the drug resistance pattern of pathogenic bacteria isolated from clinical patients of hospitals in Chenzhou region,and to provide the evidence for rational use of antibiotics in clinical practice. Methods Various specimens for culture were collected from clinical infection patients hospitalized in 12 hospitals of Chenzhou region from January 2006 to December 2010.Bacterial identification and antibiotic susceptibility testing were performed using semi-automatic analysis system produced by Huizhou Sunshine Biological Corporation.And all the result data were statistically analyzed. Results A total of 22,327 strains of bacteria were separated during the five-year period.The drug resistance rates of the principal gram-negative bacilli to first-and second-generation cephalosporin were generally more than 70%,and those to third-generation cephalosporin and cefepime were more than 50%.The principal gram-negative bacilli were highly susceptible to carbapenems and compound preparation containing Beta-lactamase inhibitor.The ratios of ESBLs-producing Escherichia coli and Klebseilla pneumonia were 39.1% and 44.0%,respectively.The drug resistance rate of staphylococcus for penicillin and chloramphenicol reached 91.6%.The resistance rates to cephalosporin and quinolone were 30%～60%.No vancomycin resistant strains were found.The separated rates of MRSA and MRSCN were 54.9% and 42.0%,respectively.The resistance rate of streptococcus to macrolideantibiotic was above 50%;moreover,streptococcus was susceptible to the other antibiotics.The drug resistance rates of enterococcus for chloramphenicol,vancomycin,and rifamycin were less than 30%,but higher resistant rates for other antibiotics were found.13,957 strains of multiple drug-resistant bacteria were detected,with the separated rate of 62.5%. Conclusions The drug resistance of bacteria isolated from various specimens collected from clinical infection patients in Chenzhou region is serious,especially the higher isolated rates of multiple drug-resistant bacteria.Special attention should be paid to this issue by all kinds and all levels of medical administrative departments." @default.
- W2374103634 created "2016-06-24" @default.
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- W2374103634 date "2011-01-01" @default.
- W2374103634 modified "2023-09-23" @default.
- W2374103634 title "Analysis on Distribution Characteristics and Drug Resistance of Pathogenic Bacteria Isolated form Clinical Infection Patients in Chenzhou Region" @default.
- W2374103634 hasPublicationYear "2011" @default.
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