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- W2374137726 abstract "Objective:To investigate the change of plasma MCP-1 in type 2 diabetic patients with coronary heart disease.Methods: One hundred and seventy-six patients with type 2 diabetes mellitus were chosen and divided into 2 groups: DM group(101cases) and DM+CHD group(75cases).In addition,70 healthy people were chosen as control group.The level of plasma MCP-1 was measured by the method of sandwich ELISA.Results: Compared with that in control group,the level of MCP-1 was significantly increased in both DM+CHD group and DM group.Level of MCP-1 was higher in DM+CHD group than that in DM group.The MCP-1 content was significantly correlated with the levels of SBP、 HDL-C、 HbA1C、 FBG.The Gensini score which reflects the degree of severity of coronary artery narrowing was significantly correlated with the level of MCP-1,and multiple logistic regression analysis showed that MCP-1 was an independent risk factor of CHD in diabetic patients.Conclusion:The level of MCP-1 is significantly increased in diabetic patients and correlated with degree of the coronary artery narrowing,and moreover,is an independent risk factor for type 2 diabetes mellitus patients with CHD." @default.
- W2374137726 created "2016-06-24" @default.
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- W2374137726 date "2008-01-01" @default.
- W2374137726 modified "2023-09-28" @default.
- W2374137726 title "Change of Plasma MCP-1 in Patients With Type 2 Diabetes Complicated With Coronary Heart Disease" @default.
- W2374137726 hasPublicationYear "2008" @default.
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