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- W2374211594 abstract "Objective To observe the therapeutic and adverse effects of large dosage of inhaled beclometasone on the patients with severe asthma. Methods Thirty eight patients with severe asthma were equally randomized into group A and group B. Large doses of beclometasone were inhaled with a spacer in group A and without a spacer in group B for 8 to 14 weeks. Peak expiratory flow (PEF), symptom scores and side effects were recorded before and after the treatment. Results Inhalation of large dose of beclometasone significantly ameliorated bronchial obstruction and other clinical symptoms. The major side effects of this therapy were fungus infection of the oral cavity, vocal hoarseness and laryngeal discomfort. Nevertheless all of the side effects could be alleviated with the usage of a spacer and the therapeutic effect of beclometasone was intensified at the same time. Conclusion Large dosage of inhaled beclometasone can alleviate the clinical manifestation and improve lung functions of the patients with severe asthma." @default.
- W2374211594 created "2016-06-24" @default.
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- W2374211594 date "2000-01-01" @default.
- W2374211594 modified "2023-09-25" @default.
- W2374211594 title "Treatment of severe asthma with large dosage of inhaled beclometasone" @default.
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