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- W2374263658 abstract "Objectives To evaluate the change of plasma homocysteine level(Hcy),CD11b/CD18 expressions,C-reactive protein(CRP)and white blood cells(WBC)in patients with acute coronary syndrome (ACS). Methods The study included 75 ACS patients and 35 healthy control objects based on their clinical situations, electrocardiogram, cardiac enzyme, troponin T, and 35 patients with stable angina pectoris (SAP) based on cardioangiography. Hcy levels were measured by enzyme immunoassay and leukocyte surface adhesive molecules CD11b/CD18 expressions were analyzed by immunofluorescence flow cytometry. CRP,WBC,blood glucose, lipids and blood pressure were also measured and analyzed. Results ① The mean levels of blood glucose, total cholesterol, low density lipoprotein-cholesterol were higher and high density lipoprotein-cholesterol was lower in both ACS and SAP groups than those in control,while there were no differences between ACS and SAP groups. Systolic blood pressure and diastolic blood pressure in ACS were higher than those in control; ② The levels of Hcy, CD11b,CD18,CRP and WBC were markedly increased in ACS than those in SAP (P0.05). Despite of the high level of HCY in SAP,there was no difference of other parameters between SAP and control. Conclusions ①Blood glucose,lipids and blood pressure are risk factors for coronary heart disease including ACS and SAP; ② Inflammation may be one from important reasons for ACS. Homocysteine,leukocytes and their CD11b/CD18 expressions and CRP are involved in the occurrence of ACS together." @default.
- W2374263658 created "2016-06-24" @default.
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- W2374263658 date "2007-01-01" @default.
- W2374263658 modified "2023-09-25" @default.
- W2374263658 title "Changes of homocysteine and adhesion molecules in patients with acute coronary syndrome" @default.
- W2374263658 hasPublicationYear "2007" @default.
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