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- W2374265409 abstract "Objective To establish the partial spinal cord injury model with atlantoaxial dislocation in rabbits by surgical operation and observe the early pathological changes of apoptotic death of neural cells.Methods The model of partial spinal cord injury induced by atlantoaxial anterior dislocation in rabbits was established.Terminal deoxynuleotidyl-mediated nick end labeling(TUNEL) was used to detect the expression of neuyocytic apoptosis in the injured site 6,24 and 72 hours after operation.Results A great number of TUNEL-positive cells were observed in the injured site at 6 hours after operation,reached the peak 24 hours after operation,and continued until 72 hours after operation.The numbers of the apoptosis neurocytes were increased compared with the sham-operated control group at all the timepoints(P0.05).These numbers were higher at 24 hours after operation than those at 6 hours and 72 hours after operation(P0.05).Conclusion Partial spinal cord injury model with atlantoaxial dislocation in rabbits can be successfully established by surgical operation.Spine cord injury gradually gets worse after reliable fixation of atlantoaxial(no reset) and the apoptosis of neural cells occur extensively." @default.
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- W2374265409 date "2012-01-01" @default.
- W2374265409 modified "2023-09-22" @default.
- W2374265409 title "Early Neurocyte Apoptosis of Rabbits with Spinal Cord Injury Induced by Atlantoaxial Anterior Dislocation" @default.
- W2374265409 hasPublicationYear "2012" @default.
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