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- W2374294562 abstract "Objective To investigate the effect of quercetin on the proliferation and apoptosis of rat mesangial cells.Methods Rat mesangial cells were incubated with different concentration of quercetin.Cell proliferation was assessed by MTT colorimetric assay.Cell cycle and apoptosis were analyzed by flow cytometry.Results Administration of 5-30μmol/L quercetin into culture medium could significantly inhibit mesangial cell proliferation in a dose and time-dependent manner;subsequently increased the cells in G_0/G_1 phase and decreased the cells in S phase.High dose of quercetin also could induce mesangial cells to apoptosis.Conclusion Quercetin could significantly inhibit mesangial cell proliferation and make it arrest in G_0/G_1 phase and induce the cell apoptosis." @default.
- W2374294562 created "2016-06-24" @default.
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- W2374294562 date "2006-01-01" @default.
- W2374294562 modified "2023-09-24" @default.
- W2374294562 title "Effect of quercetin on proliferation,apoptosis and cell cycle of rat mesangial cells cultured in vitro" @default.
- W2374294562 hasPublicationYear "2006" @default.
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