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- W2374311147 abstract "Objective To calculate the radioactivity disposition in endovascular irradiation for preve nting restenosis after angioplasty and to give an empirical formula easy to use . Methods ①The process of intravascular brachytherapy with 90 Y, 188 Re or 32 P filled balloon was simulat ed with the computer program based on beta particle dose point kernel; and the a bsorbed dose distribution was calculated. ②The curve of absorbed dose rate vers us the outer radius of the balloon and the penetrating depth in the vessel wall were fitted to a function with non-linear least squares method and an empirical formula easy to use was built. Results The absorbed doses distribu ting along the radial direction of the standard balloon showed that the peak val ue was inside the balloon, and the inflexion of the dose curve was at the endoth elial surface of the vessel. The dose decreased sharply with the radial distance approximately in an exponential manner in the vessel wall. The relationship of absorbed dose to radiation time, initial radioactivity, tissue depth, balloon ou ter radius were all expressed with an empirical formula. Conclusions The dose decreases sharply within the vessel wall, and that is very advantageo us for focusing radiation energy on the vessel wall and preventing damaging dist ant normal tissue. Using the empirical formula, according to the required absorb ed dose, the required radiation time can be easily calculated for clinical purpo se." @default.
- W2374311147 created "2016-06-24" @default.
- W2374311147 creator A5073712836 @default.
- W2374311147 date "2003-01-01" @default.
- W2374311147 modified "2023-09-25" @default.
- W2374311147 title "Calculation of radioactivity disposition from beta nuclide filled balloon in in travascular brachytherapy" @default.
- W2374311147 hasPublicationYear "2003" @default.
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