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- W2374348514 abstract "Objective To investigate the value of N-terminal-pro-brain natriuretic peptide(NT-proBNP) concentration in pleural fluid in the diagnosis of cardiogenic hydrothorax.Methods The concentration of NT-proBNP in plasma and pleural fluid were detected respectively in 40 patients with congestive heart failure accompanied by hydrothorax(observation group) and 32 ones with normal heart function accompanied by hydrothorax(control group),and the difference in NT-proBNP concentration was compared between two groups.Taking NT-proBNP concentration as cutpoint when it was higher than 1500 pg/mL,its sensitivity,specificity and Youden index in the diagnosis of cardiogenic hydrothorax were calculated.Results The comparison of plasma NT-proBNP concentration between observation group[(3829±583) pg/mL]and control group[(274±113) pg/mL]showed a statistical difference(P0.05).The comparison of pleural fluid NT-proBNP concentration between observation group[(2874±952) pg/mL]and control group[(447±152) pg/mL]showed a statistical difference(P0.05).The proportion of patients with higher NT-proBNP concentration(1500 pg/mL) in pleural fluid in observation group(90.0%,36/40) was significantly higher than that in control group(12.5%,4/32,P0.05).The sensitivity,specificity and Youden index were,respectively,90.0%,87.5% and 77.5% when pleural fluid NT-proBNP concentration(1500 pg/mL) was taken as cutpoint for diagnosing cardiogenic hydrothorax.Conclusion A higher NT-proBNP concentration in pleural fluid is helpful to the diagnosis of cardiogenic hydrothorax." @default.
- W2374348514 created "2016-06-24" @default.
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- W2374348514 date "2012-01-01" @default.
- W2374348514 modified "2023-09-23" @default.
- W2374348514 title "Significance of detection of NT-proBNP concentration in pleural fluid in patients with congestive heart failure accompanied" @default.
- W2374348514 hasPublicationYear "2012" @default.
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