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- W2374441480 abstract "Objective: To investigate the effect and mechanism of bi-target RNA interference on survivin expression of survivin in transfected colorectal SW620 cells. Methods: The bi-target RNA interference plasmid for survivin gene was constructed,SW620 cells were transfected with plasmid survivin1,survivin2 and survivin 1+2,and Western blotting was used to observe the protein levels. Results: DNA sequencing confirmed the plasmid for survivin gene was successfully constructed. Western bloting assay indicated that the expression of survivin protein in SW620 cells interfered by survivin was significantly lower than those in normal control. Conclusion: The bi-target RNA interference can lower the expression of survivin protein,and provide valuable reference for the treatment of colorectal carcinoma." @default.
- W2374441480 created "2016-06-24" @default.
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- W2374441480 date "2008-01-01" @default.
- W2374441480 modified "2023-09-24" @default.
- W2374441480 title "Experimental Study on Treatment of Colorectal Carcinoma with Bi-target Survivin siRNA" @default.
- W2374441480 hasPublicationYear "2008" @default.
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