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- W2374456212 abstract "Objective To explore the molecular mechanisms underlying neurotransmitter releasing from synaptic vesicles and confirm the exact effect in the process by proposing relative assumptions molecular mechanisms.MethodsBy using the verapamil(the antagonist against Ca2+ ion channel) and H-89(the antagonist against PKA) to work selectively on the toads' isolated sciatic nerve,we could confirm the assumption in the consequence of observations on how much the muscle shrink after being stimulated.ResultsThe amplitude of Ca2+ group's shrinkage curve was larger than the control group's(P0.05);The amplitude of the verapamil group is smaller than the one of control group's(P0.05).The amplitude of the H-89 group was smaller than that of the control group(P0.05).The amplitude of the Mg2+ group was smaller than that of the control group(P0.05).ConclusionCa2+ can stimulate neurotransmitter to release from synaptic vesicles.In the process of releasing,verapamil,H-89 and Mg2+ play negative roles which inhibit neurotransmitter releasing." @default.
- W2374456212 created "2016-06-24" @default.
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- W2374456212 date "2009-01-01" @default.
- W2374456212 modified "2023-09-24" @default.
- W2374456212 title "The research on the effect of Ca~(2+) in sciatic nerve's synaptic vesicles by detecting reactions of gastrocnemius" @default.
- W2374456212 hasPublicationYear "2009" @default.
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