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- W2374516238 abstract "Objective:Summarizing the10-years treatment effect by using of differentiation induction agents in combination with cytotoxic agents on adult patients with acute premyeloˉcytic leukemia(APL)and analyzing the prognostic factors which influence the treatment effecˉtiveness.Methods:Comparing the group of39patients(experimental group)treated with all-trans retinoic acid(ATRA)and cytotoxic agents from Nov.1988to July1999with the group of APL23patients(control group)treated with traditional chemotherapy before Nov.1988;Anaˉlyzing the factors liable to cause patients to relapss.Results:The complete remission rate(CR),3-years disease-free survival(DFS),and5-years overall survival(OS)of the experimental group and control group are82.0%vs26.0%(P0.01);47.2%vs7.4%(P0.05);and42.4%vs7.4%(P0.05),respectively.Conclusion:By applying the new method with ATRA plus chemotherapy agents to treat APL on induction,consolidation and maintenance,the CR,DFS,OS and curing effectiveness are more effective than the traditional one,having greatly improved the APL patients'outcome." @default.
- W2374516238 created "2016-06-24" @default.
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- W2374516238 date "2004-01-01" @default.
- W2374516238 modified "2023-09-25" @default.
- W2374516238 title "Observation on therapeutic effect of combination treatment on adult patients with acute premyelocytic leukemia" @default.
- W2374516238 hasPublicationYear "2004" @default.
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