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- W2374559024 abstract "OBJECTIVE:To observe the impact of ethylacetate extract from Squilla oratoria on cell proliferation and cycle in nasopharyngeal cell line CNE-2Z.METHODS:The inhibitory rate of the proliferation was detected by MTT assay.The DNA synthesis activity was determined with -TdR labeling technique.The cell cycle was analyzed by flow cytometry.RESULTS:The ethylacetate extract of Squilla oratoria remarkably inhibited the proliferation and DNA synthesis of CNE-2Z cells in time and does-dependent manner.When the concentration of the ethylacetate extract was above 400μg/mL,the inhibitory rate of incoporation was higher than that of 5-Fu(20 μg/mL).With the concentration of the ethylacetate extract increasing the proportion of G1 phase and G2/M phase decreased and S phase increased(P0.01).CONCLUSIONS:The ethylacetate extract can inhibit the proliferation of CNE-2Z cells.The effect mechanism may be related to arresting the cell cycle in S phase." @default.
- W2374559024 created "2016-06-24" @default.
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- W2374559024 date "2010-01-01" @default.
- W2374559024 modified "2023-09-28" @default.
- W2374559024 title "Impact of ethylacetate extract from Squilla oratoria on cell proliferation and cycle in nasopharyngeal cell line CNE-2Z" @default.
- W2374559024 hasPublicationYear "2010" @default.
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