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- W2374591481 abstract "In isolated rabbit pulmonary artery mnifidiPine(m-Nif) and nifidiPine(Nif) inhibited the contraction induced by calcium and shifted the concentration-response curve nonparallely to right.The values of PD'2 are 6.14 and 5.89,IC50 values are 0.93 μmol·L-1 and 1.13 μmol·L11 respectively.In isolated rat pulmonary artery and aorta,the respones of pulmonary artery and aorta to KCl are higher in hypertension than in normotension(P0.01).m-Nif and Nif inhibited pulmonary artery and aorta,IC50 values are lower in hypertensive rats than in normal rats.There is no evident difference between IC50values in treated-hypertensive rats and those in normal rats.These results indicate that the action of mNif is simlar to that of Nif,the relaxant responses of pulmonary artery and aorta to m-Nif and Nif increase,after treated with m-Nif or Nif,the relaxant responses of pulmonary artery and aorta to m-Nif and Nif are restored and near to those of normal rats." @default.
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- W2374591481 date "1996-01-01" @default.
- W2374591481 modified "2023-09-28" @default.
- W2374591481 title "Calcium-antagonistic effects of m-nifdipine on isolated pulmonary artery of rabbits and renovascular hypertensive rats" @default.
- W2374591481 hasPublicationYear "1996" @default.
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