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• W2374597228 abstract "Objective To investigate the levels of reactive oxygen species (ROS) in expressed prostatic secretion ( EPS) in patients with chronic prostatitis ( CP) , and to study the relationship between ROS and mechanism of CP. Methods According to NIH classification, ROS levels were measured by coloration in the EPS of 87 CP patients (10 cases of typeⅡ, 30 of typeⅢ, 30 of typeⅢB and 17 of typeⅣ) and 26 normal individuals. Urine was cultured and EPS was studied according to 2-glass test. Results The ROS values were in normal distribution among the groups. The mean ?standard error of ROS levels was higher inⅡ(233. 1±56. l)U/ml,ⅢA (180.5±70. 7)U/ml,ⅢB (156. 8±38.9)U/ml andⅣgroups ( 124. 9±34. 1) U/ml than that in controls (87.9±26.3)U/ml, showing a tendency from high to low values. There were statistically significant differences between any 2 groups (P 0.05) ,but no statistically significant difference betweenⅢA CP/CPPS andⅢB CP/CPPS groups (P 0. 05). There was a positive correlation between ROS level and WBC count in EPS ( r = 0. 275 , P = 0. 01). The 87 CP patients were divided into 4 groups by WBC count in EPS. The mean±standard error of ROS levels was ( 153. 7±35. 9) U/ ml in 0 -9 WBC/HP group ( n = 30) ; ( 153. 3±44. 8) U/ml in 10 - 19 WBC/HP group ( n = 16) ; (163.7±57. l)U/ml in 20 -49 WBC/HP group (n =24) ;(205.3±92.9)U/ml in 50 WBC/HP group ( n = 17). There were statistically significant differences between the 4 groups (F = 3. 297 ,P 0.05) . There was a negative correlation between ROS levels and lecithin in EPS( r = - 0. 31 ,P 0. 01). The 87 CP patients were divided into 4 groups by lecithin contents. The mean±standard error of ROS levels was ( 187. 8±76. 4) U/ml in ( +) group ( n =22) ;( 173. 6±53. 7) U/ml in ( + +) group (n = 32) ; (160. 0±49. 7) U/ ml in( + + + )group (n =24) ; ( 117. 0±43. 5) U/ml in ( + + + +) group (n =9). There were statistically significant differences between the 4 groups ( F = 3. 363 , P 0. 05 ). Conclusions The levels of ROS are elevated in EPS of CP patients, and may be considered as mediators of inflammatory response in the prostate. ROS in EPS can serve as the objective parameters for the diagnosis of CP and as a novel means to evaluate the severity of CP." @default.
• W2374597228 created "2016-06-24" @default.
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• W2374597228 date "2006-01-01" @default.
• W2374597228 modified "2023-09-24" @default.
• W2374597228 title "Reactive oxygen species levels in expressed prostatic secretion in patients with chronic prostatitis" @default.
• W2374597228 hasPublicationYear "2006" @default.
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