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- W2374664662 abstract "Purpose:To investigate the expression and mechanism of antioncogene P53 mRNA and its protein in human adrenal pheochromocytoma.Methods:In situ hybridizaiton (ISH) was employed to detect P53 mRNA in pheochromocytoma.P53 protein was examined by SP immunohistochemistry.Results:ISH showed the expression of P53 mRNA in 29 cases of pheochromocytomas was 24.1 % (7/29) and in 7 cases of malignant pheochomocytomas was 14.3 % (1/7).The expression of P53 protein in 29 cases of pheochromocytomas was 79.3 % (23/29) and in 7 cases of malignant pheochromocytomas was 71.4 % (5/7).Conclusions:The mutation of P53 gene might be very important in and responsible for pathogenesis of pheochromocytoma." @default.
- W2374664662 created "2016-06-24" @default.
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- W2374664662 date "2000-01-01" @default.
- W2374664662 modified "2023-09-25" @default.
- W2374664662 title "Expression of antioncogene P53 mRNA and its protein in human adrenal pheochromocytoma" @default.
- W2374664662 hasPublicationYear "2000" @default.
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