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- W2374668745 abstract "Objective: To study Zn content, Zn- linking antioxidant, and the relationship between acute Zn deficiency and multiple organ failure caused by severe trauma. Methods: We established the model of rabbit after slight and severe trauma, detected the level of Zn and Cu/Zn-SOD in serum and liver and MT in liver before trauma and twelve hours, thirty-six hours, six days, nine days, two weeks, four weeks after trauma. Results: In slight trauma group Zn content in serum decreased significantly in the first six days,17.23 ±1.48 umol/L(x±s), compared with the normal 23.8±15.08 umol/L, P0.05. In severe trauma group, Zn was 7.87±2.92 umol/L in the first two weeks, P0.01 ,and 12.14±9.46 umol/L in the twenty-eighth day , P0.05.Among the severe trauma group, seven rabbits died (the mortality was 35%), and Zn content of the dead animals was significantly lower than the living animals in the first day after trauma,P0.05. Zn content of liver increased in severe trauma group. The level of Cu/Zn-SOD of serum increased obviously (P0.01) and was higher than control group for two weeks, P0.05. The level of Cu/Zn-SOD and MT of liver also occurred the changes. Conclusion: Thus there were a series of changes in function and metabolism caused by acute trace element deficiency after severe trauma, and this may be one of the important causes of hospital infection and multiple organ failure, even death." @default.
- W2374668745 created "2016-06-24" @default.
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- W2374668745 date "2005-01-01" @default.
- W2374668745 modified "2023-09-24" @default.
- W2374668745 title "Study on Zinc Content and Antioxidant of Rabbit in Acute Phase after Severe Trauma" @default.
- W2374668745 hasPublicationYear "2005" @default.
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