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- W2374679381 abstract "Non-alcoholic fatty liver disease (NAFLD) is now the commonest liver disorder in the world. It is closely associated with the features of metabolic syndrome, particularly obesity and diabetes. More and more evidence show that insulin resistance is the key etiological factor of non-alcoholic steatohepatitis (NASH) occured in patients with metabolic syndrome. Indeed, insulin resistance can increase steatosis and subsequent accumulation of free fatty acids in liver. It can also stimulate the reaction of oxidative stress and promote lipid peroxidation as well as generation of inflammatory cytokine. Since there is no firm evidence-based medicine treatment for NAFLD, the therapy of which is currently directing at improving metabolic syndrome. A variety of novel drugs which in periods of animal tests and prophased clinical studies are worthy of paying attention to following the elucidation of mechanisms leading to NAFLD recently." @default.
- W2374679381 created "2016-06-24" @default.
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- W2374679381 date "2008-01-01" @default.
- W2374679381 modified "2023-09-24" @default.
- W2374679381 title "Update on the treatments of non-alcoholic fatty liver disease" @default.
- W2374679381 hasPublicationYear "2008" @default.
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