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- W2374711156 abstract "To detect the serum interleukin 27(IL-27) level in primary Sjgren syndrome(pSS) patients and its relations to characteristic parameters of the disease,31 patients with pSS and 31 healthy volunteers were recruited.The expression of IL-27 in peripheral blood mononuclear cells(PBMCs) and plasma were detected by RT-PCR and ELISA,respectively.The disease laboratory parameters were collected from medical records.The plasma IL-27 level and IL-27 mRNA relative expression in PBMCs of pSS patients were significantly lower than those in healthy controls(P0.05).The plasma IL-27 level was negatively correlated with serum anti-SSA antibody,serum anti-SSB antibody and IgE level,but not with serum IgG and CRP concentration,as well as ESR level.The low level of plasma IL-27 in pSS patients and the relationship with disease characteristic parameters suggested that this cytokine might be implicated in the pathomechanism of pSS." @default.
- W2374711156 created "2016-06-24" @default.
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- W2374711156 date "2012-01-01" @default.
- W2374711156 modified "2023-09-28" @default.
- W2374711156 title "Low level of plasma interleukin 27 in patients with primary Sjgren syndrome" @default.
- W2374711156 hasPublicationYear "2012" @default.
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