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- W2374720977 abstract "Objective: To explore the effect of electro-acupuncture on the learning and memory and the neuronal nitric oxide synthase(nNOS) expression in cortex of the dementia rats.Methods: Vascular dementia(VD) rat model of reperfusion following cerebral global ischemia was established by using a modified Pulsinelli-4-vessel occlusion method.All the rats were randomly divided into 4 groups: sham-operated control group,model group,electro-acupuncture group,Piracetan group.All the groups were divided into corresponding methods respectively.The expression of nNOS in cortex was detected and calculated by Leica-bx60 Image Analyzer.Y-type maze was used to measure learning and memory scores of the rats.Results : The scores of Y-type maze of the model group are apparently less than sham-operated group(P0.05),At the same time,the expression of nNOS of all treatment groups in cortex was reduced than that of model group(P0.05).The scores of Y-maze of all treatment groups is higher than those of the model group(P0.05) ,which are no difference from sham-operated.(P0.05).Conclusions: Electro-acupuncture could apparently improve the ability of learning and memory of dementia rats and the mechanism may be that acupuncture could inhibit the over-increased nNOS after cerebral ischemia to protect the neurons from decreasing." @default.
- W2374720977 created "2016-06-24" @default.
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- W2374720977 date "2008-01-01" @default.
- W2374720977 modified "2023-09-23" @default.
- W2374720977 title "Electro-acupunctural Influences on the Learning and Memory and the Expression of nNOS in cortex of Dementia Rats" @default.
- W2374720977 hasPublicationYear "2008" @default.
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